Katharina Buczek
Instead, BnOCPA is able to target and selectively activate only one kind of G protein, leading to reduced side effects and a better treatment experience for patients.
Dr. Mark Wall, the study’s lead researcher, described how this rare feature of BnOCPA has the potential to change patient care and pave the way for the development of other analgesic drugs.
“The selectivity and potency of BnOCPA makes it truly unique. We hope that with further research, it will be possible to generate potent painkillers to help patients cope with chronic pain,” Dr. Wall said.
Surprisingly, the researchers also stumbled upon this discovery unexpectedly. Professor Bruno Frenguelli, a lead investigator in the study, explained how BnOCPA’s characteristics were a positive surprise.
“This is a fantastic example of serendipity in science. We had no expectations that BnOCPA would behave differently from other molecules in its class. But, the more we looked into the drug, we discovered properties that had never been seen before,” Fenguelli recalled.
Now, the scientists are hopeful that their research will provide new avenues for medicinal chemistry in pain relief.
To read the study’s complete findings published in Nature Communications, visit the link here.
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