With these findings, the researchers have also estimated that about one in every fifty-seven thousand people carries this gene mutation.
“What’s most exciting is that this finding allows us to confirm decades of research in animals. The biological effects of adiponectin in regulating insulin sensitivity, glucose tolerance, and ceramide levels are well established in mice, and the current study shows that a loss of adiponectin impairs metabolic health in humans,” explained William Holland, one of the study’s corresponding authors.
Now, the researchers hope their discovery could open new avenues of early intervention and treatment options for affected patients.
“We can use these findings as a starting point for the development of personalized medicines that mimic the beneficial effects of adiponectin and diminishes the risk of diabetes and kidney disease,” underscored Holland.
To read the study’s complete findings, visit the link here.
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