Katharina Buczek
The team believes this finding to be crucial for current research that aims to study the benefits of immunotherapies.
“This recent discovery gives us hope that we will continue to find answers and contribute to solutions for a disease which has long afflicted all ancestries but shows greater burden in Africa,” underscored Dr. Ernest Adjei.
Additionally, the study also found that numerous African ancestry-associated genes present in normal breast tissue actually switch expressions in tumor tissue.
“These findings suggest that some ancestry-specific differences in gene expression may be in response to malignancies,” explained Rachel Martini, the study’s lead author.
In turn, the team plans to continue analyzing gene expression differences and tumor microenvironments in hopes of impacting patient treatment.
“We want to get to the bottom of the molecular features driving disparities in TNBC before we move our work into the clinical space,” said Melissa Davis, the study’s senior author.
To read the study’s complete findings, which have since been published in Cancer Discovery, visit the link here.
If true crime defines your free time, this is for you: join Chip Chick’s True Crime Tribe
The Terrifying True Tale Of The Real Annabelle Doll And What Her Reign Of Terror Looked Like
