Research Has Shown That Childhood Obesity Not Only Increases The Risk Of Type 2 Diabetes And Hypertension But Is Also Linked To Weaker Cognitive Functioning

Rawpixel.com - stock.adobe.com - illustrative purposes only, not the actual people
Rawpixel.com - stock.adobe.com - illustrative purposes only, not the actual people

Ongoing research has shown that childhood obesity not only increases the risk of diseases such as hypertension and Type 2 diabetes but also leads to a problem that’s not often discussed – declining brain health.

In a study conducted by researchers working with the Radiological Society of North America, it was found that kids with a higher body mass index (BMI) before hitting adolescence tend to exhibit weaker cognitive abilities.

“We know being obese as an adult is associated with poor brain health,” said Simone Kaltenhauser, a radiology and biomedical imagine post-graduate research fellow at the Yale School of Medicine.

“However, previous studies on children have often focused on small, specific study populations or single aspects of brain health.”

So, the team analyzed MRI data from the Adolescent Brain Cognitive Development (ABCD) study. This research involved 11,878 children aged 9 to 10 from 21 locations nationwide, ensuring a varied sample that reflects the broader population.

They omitted children with eating disorders, neurodevelopmental and psychiatric conditions, and those who had suffered traumatic brain injuries – narrowing their focus to slightly over 5,100 participants.

By utilizing BMI z-scores, which adjust for age, gender, and height to assess relative weight, they found that 21% of these children were overweight, while 17.6% were classified as obese.

Next, the researchers assessed brain health through the analysis of data from structural MRI and resting-state functional MRI (fMRI) scans, which are techniques that monitor blood flow changes. They also employed diffusion tensor imaging to investigate the structure of the brain’s white matter.

Upon adjusting for variables such as age, gender, race-ethnicity, right or left-handedness, and socioeconomic status, the team observed changes in brain structure related to higher weight and BMI z-scores in children.

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Children classified as obese showed signs of compromised white matter integrity. In particular, damage was seen in the white matter of the corpus callosum, the crucial bridge facilitating communication between the brain’s two hemispheres.

Additionally, the researchers recorded a reduction in the thickness of the brain’s cortex, which plays a vital role in cognitive functions.

“It is striking that these changes were visible early on during childhood,” explained Kaltenhauser.

“We expected the decrease in cortical thickness among the higher weight and BMI z-score children, as this was found previously in smaller subsamples of the ABCD study. However, we were surprised by the extent of white matter impairment.”

Sam Payabvash, the study’s senior author, also noted that the results of this study provide a mechanistic understanding of previous research connecting high BMI in children with reduced cognitive abilities and academic achievements.

So, Payabvash recommends ongoing observation of these children for six to 10 years to track changes in their brain development over time.

To read the study’s complete findings, visit the link here.

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Katharina Buczek graduated from Stony Brook University with a degree in Journalism and a minor in Digital Arts. Specializing ... More about Katharina Buczek
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